CNS Pharmaceuticals, Inc. - Common Stock (CNSP)

CNS Pharmaceuticals (NASDAQCNSP) a biopharmaceutical company focused on treatments for brain and central nervous system cancers, provided an update on its cash position and efforts to maintain its Nasdaq listing. The company reported a strengthened financial position, with $14 million in cash as of Feb. 26, 2025, expected to fund operations into the first quarter of 2026. CNS remains on track to announce primary data analysis for its global Berubicin trial in the first half of 2025 and plans to begin its TPI 287 clinical program by enrolling its first patient before year-end. To maintain compliance with Nasdaq’s listing requirements, the company recently executed a reverse stock split.

Cash on hand provides over one year of runway to fund expected operations

CNS Pharmaceuticals (NASDAQCNSP) announced that CEO John Climaco will present at the 18th Annual European Life Sciences CEO Forum in Zurich on Feb. 26, 2025, at 3:20 p.m. CET / 9:20 a.m. EST; management will also be available for one-on-one meetings with registered investors, and a video webcast of the presentation will be accessible on-demand through the conference presenters portal.

A new study whose findings were published in the Nature Communications journal has shown how tumor cells are changed by the environment around them. Because of these alterations, cancer cells alter their shape, thereby escaping from the tumor and spreading to other parts of the organ or body.

Webcast presentation Wednesday, February 26th at 3:20 PM CET

CNS Pharmaceuticals (NASDAQCNSP) announced its participation in the Virtual Investor Top 5 for ‘25 On-Demand Conference, where CEO John Climaco outlined five key reasons for investors and industry peers to follow the company in 2025. The presentation focused on CNS Pharmaceuticals’ advancements in developing treatments for primary and metastatic brain and central nervous system cancers, emphasizing its strategic initiatives and clinical progress for the year ahead.

On-demand video webcast now available here

In-person presentation today, February 10th at 1:15 PM ET

Live webcast discussion featuring internationally renowned Glioblastoma Multiforme (GBM) Key Opinion Leaders

CNS Pharmaceuticals (NASDAQCNSP) announced a 1-for-50 reverse stock split of its common stock, set to take effect on Feb. 21, 2025. The company’s shares will continue trading on Nasdaq under the symbol “CNSP” but with a new CUSIP number: 18978H409. The reverse split aims to increase the per-share trading price and ensure compliance with Nasdaq’s minimum share price requirement. As a result, every 50 shares of common stock will be consolidated into one, with proportional adjustments made to outstanding equity awards and warrants. No fractional shares will be issued, with cash payments provided instead. The number of authorized shares remains at 300 million, and the split will not impact stockholders’ percentage ownership, aside from adjustments for fractional shares.

HOUSTON, TX / ACCESS Newswire / February 19, 2025 / CNS Pharmaceuticals, Inc. (NASDAQCNSP) ("CNS" or the "Company"), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers in the brain and central nervous system, today announced a 1-for-50 reverse split of its common stock. Beginning on February 21, 2025, the Company's common stock will continue to trade on The Nasdaq Capital Market ("Nasdaq") on a split adjusted basis under the trading symbol "CNSP", but will trade under the following new CUSIP number: 18978H409. The reverse stock split is primarily intended to increase the Company's per share trading price and bring the Company into compliance with the Nasdaq's listing requirement regarding minimum share price.

CNS Pharmaceuticals (NASDAQCNSP) announced its participation in the 6th Glioblastoma Drug Development Summit, taking place Feb. 18-20, 2025, in Boston. Chief Medical Officer Dr. Sandra Silberman will present on Feb. 20 at 10:45 a.m. ET, discussing novel formulations of anthracyclines and taxanes designed to cross the blood-brain barrier. The company’s lead candidate, Berubicin, has completed patient enrollment in a pivotal study against glioblastoma, with primary analysis data expected in the first half of 2025. CNS Pharmaceuticals is also advancing TPI 287 and plans to engage with the FDA on trial design. Berubicin has received Fast Track and Orphan Drug Designations from the FDA.

HOUSTON, TX / ACCESS Newswire / February 18, 2025 / CNS Pharmaceuticals, Inc. (NASDAQCNSP) ("CNS" or the "Company"), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers in the brain and central nervous system, today announced it will present at the 6th Glioblastoma Drug Development Summit being held February 18-20, 2025 in Boston, MA.

Primary analysis data in potentially pivotal GBM study with lead program, Berubicin, on track for the first half of 2025

CNS Pharmaceuticals (NASDAQCNSP), a biopharmaceutical company focused on developing treatments for brain and central nervous system cancers, will participate in the BIO CEO & Investor Conference in New York on Feb. 10-11, 2025. CEO John Climaco is scheduled to present on Feb. 10 at 1:15 p.m. ET in the Royale Room. Management will also be available for one-on-one meetings, with scheduling available through the BIO CEO attendee portal.

A new study conducted by University of Liverpool scientists together with collaborators from around the world has revealed the most suitable ways through which the blood-brain barrier can be bypassed while treating neurological conditions. The blood-brain barrier has been a major challenge that has stood in the way of getting needed medicines into the brain, and this study’s findings offer solutions that could result in conditions like Alzheimer’s, Parkinson’s, epilepsy and brain tumors being treated effectively.

A team of researchers from the Chinese Academy of Scientists has discovered that a common high blood pressure medication may be useful in treating a certain brain tumor. The tumor, a craniopharyngioma, is a non-cancerous growth that usually develops near the hypothalamus and pituitary gland.

Glioblastoma multiforme is an aggressive type of cancer that primarily affects the brain. A new study has found that this cancer has an internal clock which is synced every day to capitalize on the circadian rhythm of the patient. This feature allows tumors to grow as the patient’s body releases hormones.

CNS Pharmaceuticals (NASDAQCNSP), a biopharmaceutical company developing treatments for brain and central nervous system cancers, will host a Virtual Analyst & Investor Day on December 11 from 11:30 a.m. to 1 p.m. ET. The event will feature presentations by the company’s leadership team, including CEO John Climaco, Chief Medical Officer Dr. Sandra Silberman, and VP of Clinical Operations Zena Muzyczenko, alongside key opinion leaders Dr. Michael Weller, Dr. Samuel Goldlust, and Dr. Erin Dunbar. Discussions will focus on glioblastoma multiforme (“GBM”), updates on the clinical development of Berubicin, and regulatory strategies for the company’s second asset, TPI 287. A live video webcast and replay will be available on the company’s website.

Central nervous system and brain cancers accounted for 248,500 deaths globally in 2022. In America, roughly 90,000 brain tumors are diagnosed annually, with data from the American Cancer Society showing that over 25,000 of these tumors are cancerous. It is projected that there’ll be an estimated 25,400 new cases of central nervous system and brain cancers in 2024.

CNS Pharmaceuticals (NASDAQCNSP) announced updated results from its ongoing pivotal trial evaluating Berubicin, a novel anthracycline crossing the blood-brain barrier, against Lomustine in recurrent glioblastoma multiforme (“GBM”). Presented at the 29th Annual Meeting of the Society for Neuro-Oncology, the data show balanced patient demographics and safety profiles between the study arms, with Berubicin showing comparable adverse event rates and promising potential to improve overall survival (“OS”), the trial’s primary endpoint. With enrollment completed at 252 patients, CNS expects to report primary analysis data in early 2025. Berubicin holds FDA Fast Track and Orphan Drug Designations, underscoring its significance in advancing GBM treatment options.

Poster presented at the 29th Annual Meeting of the Society for Neuro-Oncology (SNO 2024)

CNS Pharmaceuticals (NASDAQCNSP) announced that its abstract on the pivotal trial of Berubicin, a novel treatment for glioblastoma multiforme (“GBM”), has been selected for poster presentation at the 29th Annual Meeting of the Society for Neuro-Oncology. The presentation, led by Chief Medical Officer Dr. Sandra Silberman, will provide updates on the randomized, controlled CNS-201 trial comparing Berubicin to Lomustine after first-line GBM therapy. The session will take place on Nov. 22, 2024, at the George R. Brown Convention Center in Houston, TX, during the Poster and Networking Session.

HOUSTON, TX / ACCESSWIRE / November 18, 2024 / CNS Pharmaceuticals, Inc. (NASDAQCNSP) ("CNS" or the "Company"), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers in the brain and central nervous system, today announced that its abstract has been selected for poster presentation at the 29th Annual Meeting of the Society for Neuro-Oncology being held November 21-24, 2024 in Houston, TX.

CNS Pharmaceuticals (NASDAQCNSP) reported Q3 2024 financial results and highlighted clinical advancements, including the ongoing potentially pivotal trial of Berubicin, a targeted chemotherapy for recurrent glioblastoma multiforme (“GBM”). Enrollment of 252 patients was completed, with primary analysis data expected in the first half of 2025. Berubicin, which crosses the blood-brain barrier, has received Fast Track and Orphan Drug Designations from the FDA. The company also licensed TPI 287, a late-stage candidate for brain malignancies, with plans for FDA engagement on future studies. CNS ended the quarter with $7.0 million in cash and additional funding, ensuring operations through Q2 2025.